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I remember when I started itching horribly in my senior year of college. It was the first time when I got hospitalized for over 10 days. Then the docs managed to help me somehow and diagnosed me with some liver disorder. Then, almost twelve years later, the symptoms reappeared and I was taken to emergency room with unbearable pain and constant vomiting. This time the doctors were more precise and diagnosed me with primary biliary cirrhosis. No need to say it was horrible news. But with Ursodiol that I've been prescribed with life is not that grey and gloomy. The medication is naturally very effective!
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The preparation contains the active substance Ursofalk ursodeoxycholic acid, which is present in some amount in human bile, but in some human liver synthesis of ursodeoxycholic acid and its contents, respectively, into the bile is reduced.

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This exploratory study aims at assessing whether a protective effect of the combination of pentoxifylline, ursodeoxycholic acid and enoxaparin can be demonstrated in a limited number of patients with liver metastases of colorectal cancer after HDR brachytherapy.

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Trade names for ursodiol include "Actigall" (typically available as 300 mg capsules) and "URSO" (typically available as 250 mg tablets) or "URSO-Forte" (available as 500 mg tablets).

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The diagnosis of primary biliary cirrhosis starts with liver function test.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

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Patients in group A received orally for 6 months: celecoxib (Celebrex, Pfizer, New York, NY, USA) 400 mg twice daily (once daily during the first 2 weeks), in combination with UDCA (Ursofalk, Dr Falk Pharma, Freiburg, Germany).

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Microbial biotransformation of the drug and its metabolites occurs when they leave the enterohepatic circulation, and is responsible for high levels of faecal lithocholic and 7-ketolithocholic acids during ursodeoxycholic acid therapy.

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In the treatment of gallstones with extracorporeal shock-wave lithotripsy, the bile acid ursodiol is administered to dissolve the gallstone fragments.

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